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Natural History (NH) studies are an important tool for understanding the etiology, range of manifestations, and progression of rare diseases. Well conducted NH studies can yield information on biomarkers and other correlates of clinical outcome. Especially for ultra-rare conditions where the disease is little understood, the Natural History plays a crucial role as it will set the baseline for future clinical trials.

At orphan reach, we know about the importance of reaching out to patients in the remotest locations and are familiar of collecting data from living and deceased patients across the globe.

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